Have a look at the exciting publications generated in collaboration with several bdc partners.

Peer reviewed journal articles
A specific miRNA signature in the peripheral blood of glioblastoma patients

Roth P, Wischhusen J, Happold C, Anoop Chandran P et al. (2011)

J Neurochem., doi: 10.1111/j.1471-4159.2011.07307.x. [Epub ahead of print]

read more »

Stable serum miRNA profiles as potential tool for non-invasive lung cancer diagnosis

Keller A, Leidinger P, Gislefoss R, Haugen A, Langseth H et al. (2011)

RNA Biol., Volume 8, Issue 3, May/June 2011

read more »

Specific peripheral miRNA profiles for distinguishing lung cancer from COPD

Leidinger P, Keller A, Borries A, Huwer H, Rohling M et al. (2011)

Lung Cancer. 2011 Mar 7

read more »

The intestinal factor Tff3 and a miRNA network regulate murine caloric metabolism

Shah A, Leidinger P, Keller A, Wendschlag A, Backes C et al. (2011)

RNA Biol., Volume 8, Issue 1, Pages 77–81, January/February 2011

read more »

MicroRNA signatures in total peripheral blood as novel biomarkers for acute myocardial infarction

Meder B, Keller A, Vogel B, Haas J, Sedaghat-Hamedani F et al. (2010)

Basic Research in Cardiology, DOI: 10.1007/s00395-010-0123-2

read more »

High-throughput miRNA profiling of human melanoma blood samples

Petra Leidinger, Andreas Keller, Anne Borries, Jorg Reichrath, Knuth Rass, Sven U. Jager, Hans-Peter Lenhof and Eckart Meese (2010)

BMC Cancer 2010, 10:262, doi:10.1186/1471-2407-10-262

read more »

miRNAs in lung cancer - Studying complex fingerprints in patient's blood cells by microarray experiments

Andreas Keller, Petra Leidinger, Anne Borries, Anke Wendschlag, Frank Wucherpfennig, Matthias Scheffler, Hanno Huwer, Hans-Peter Lenhof and Eckart Meese (2009)

BMC Cancer 2009, 9:353, doi:10.1186/1471-2407-9-353

read more »

A dictionary on microRNAs and their putative target pathways

Christina Backes, Eckart Meese, Hans-Peter Lenhof and Andreas Keller

Nucleic Acids Research 2010, 1-11, doi:10.1093/nar/gkq167

read more »

Multiple Sclerosis: MicroRNA Expression Profiles Accurately Differentiate Patients with Relapsing-Remitting Disease from Healthy Controls

Andreas Keller, Petra Leidinger., Julia Lange, Anne Borries, Hannah Schroers, Matthias Scheffler, Hans-Peter Lenhof, Klemens Ruprecht, Eckart Meese

PLoS ONE, October 2009, Volume 4, Issue 10, e7440

read more »

Invited journal articles
Neue Biomarker: Mikro-RNA-Muster in Patientenblut

Petra Leidinger, Andreas Keller, Hans-Peter Lenhof, Eckart Meese

Biospektrum, 02.10, 16. Jahrgang, S. 192-194

miRNA Biomarkers From Blood – A Promising Approach for Minimally Invasive Diagnostic Testing

J. Lange, P. Leidinger, T. Oehler, A. Keller, E. Meese

Geburtsh. Frauenheilk. 2010; 70: 137–141

microRNA-Profile als Diagnosemethode

Dr. A. Keller, Prof. Dr. H-P. Lenhof, Dr. I. Amarantos, Dr. A. Bauer, N. Giese, Dr. J. Hoheisel, Dr. P. Leidinger, Prof. Dr. E. Meese

Laborwelt, 11. Jahrgang , Nr. 1/2010, 33

Conference Contributions
Talk C07.4: A new approach for ovarian cancer screening - characterization of miRNA profiles in peripheral blood (read more)

S. F. M. Häusler [1], A. Keller [2], A. Chandran [3], J. Wischhusen [4]

[1] Universitäts-Frauenklinik Würzburg, Würzburg, Germany, [2] Biomarker Discovery Center Heidelberg and febit biomed GmbH, Heidelberg, Germany, [3] Graduate School for Life Sciences, Universitäts-Frauenklinik Würzburg, Würzburg, Germany, [4] Interdisciplinary Centre for Clinical Research, Universitäts-Frauenklinik Würzburg, Würzburg, Germany.

European Human Genetics Conference 2010
Session C07. Cancer Genetics
Mon, Jun 14, 1:15 - 2:45 PM, Gothenburg, Sweden

Poster: Dynamic miRNA profiles in human diseases

Andreas Keller [1], Anke Wendschlag [1], Petra Leidinger [2], Andrea Bauer [3], Jörg Hoheisel [3], Peer Staehler [4], Eckart Meese [2]

[1] Biomarker Discovery Center Heidelberg, Germany, [2] Department of Human Genetics, Medical School, Saarland University, Homburg, Germany, [3] Division of Functional Genome Analysis, German Cancer Research Center, Heidelberg, Germany, [4] febit biomed gmbh, Heidelberg, Germany

European Human Genetics Conference 2010
12-15 June 2010, Gothenburg, Sweden

Poster: New set of potential tumor marker by miRNA Profiling in human Pancreatic Cancer

A. Bauer [1], N. Giese [2], A. Keller [3], M. Bier [1], M.W. Büchler [2], and J.D. Hoheisel [1]

[1] B070, Division of Functional Genome Analysis, DKFZ Heidelberg, [2] Department of Surgery, Universitätsklinikum Heidelberg, [3] febit GmbH Heidelberg

European Human Genetics Conference 2010
12-15 June 2010, Gothenburg, Sweden

Poster: NBS-NGS: an ultra-throughput selective next-generation sequencing method for clinical diagnostics

Abdou ElSharawy [1], [3], [4], Nadine Schracke [2], [3], Andreas Keller [2], Michael Forster [1], Ingo Thomsen [1], Markus Schilhabel [1], Philip Rosenstiel [1], Stefan Schreiber [1], Peer F. Stähler [2], Ramon Güimil Garcia [2] and Andre Franke [1]

[1] Institute of Clinical Molecular Biology (ICMB), Christian-Albrechts-Universität (CAU) Kiel, Schittenhelmstrasse 12, 24105 Kiel, Germany, [2] febit biomed GmbH, Im Neuenheimer Feld 519, 69120 Heidelberg, Germany, [3] equal contribution, [4] corresponding author

Human Genetics Conference 2010
12-15 June. 2010, Gothenburg, Sweden

Poster: Targeted Next Generation Sequencing Pipeline for Large-scale Genomic Studies

Peer Stähler [1], Anne Borries [1], Dr. Matthias Scheffler [1], Yang Chen [1], Dr. Andreas Keller [2]

[1] febit biomed gmbh, Im Neuenheimer Feld 519, 69120 Heidelberg, Germany, [2] Biomarker Discovery Center Heidelberg, Im Neuenheimer Feld 519, 69120 Heidelberg, Germany

Human Genetics Conference 2010
12-15 June. 2010, Gothenburg, Sweden

Specific miRNA fingerprints in patients' blood samples as novel diagnostic tool.

Dr. A. Keller 2nd Annual Meeting of NGFN-Plus and NGFN-Transfer in the Program of Medical Genome Research,

26-28 Nov. 2009, Berlin